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SOX-10 (EP268) Rabbit Monoclonal Primary Antibody

品牌
Sigma-Aldrich
货号
383R-1
包装型号
规格纯度
价格
2389.39 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Sry-related HMG-BOX gene 10 (SOX-10) is a nuclear transcription factor that participates in neural crest development and in the specification and differentiation of cells of melanocytic lineage.1 It has been recently shown to be a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes.2 SOX-10 was expressed by metastatic melanomas in sentinel lymph nodes, but not by other lymph node components such as dendritic cells which usually express S100 protein. Anti-SOX-10 has been shown to be superior to all other immunostains in detecting residual invasive and in situ melanoma.1-5 Anti-SOX-10 is also a useful marker in detecting both the in situ and invasive components of desmoplastic melanoma.6 It is known that the commonly used melanoma markers, anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas5 while it has been reported that anti-SOX-10 was moderately to strongly expressed in almost all desmoplastic melanomas.2 SOX-10 is diffusely expressed in schwannomas and neurofibromas. SOX-10 presence was not identified in any other mesenchymal and epithelial tumors except for myoepitheliomas and diffuse astrocytomas.2

质量


IVD

IVD

IVD

RUO

联系

SOX-10 Positive Control Slides, Product No. 383S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平500
100
偶联物unconjugated
抗体形式culture supernatant
antibody product typeprimary antibodies
克隆EP268, monoclonal
描述 (For In Vitro Diagnostic Use in Select Regions (See Chart))
形式buffered aqueous solution
species reactivityhuman
包装vial of 0.1 mL concentrate (383R-14)
vial of 0.5 mL concentrate (383R-15)
bottle of 1.0 mL predilute (383R-17)
vial of 1.0 mL concentrate (383R-16)
bottle of 7.0 mL predilute (383R-18)
manufacturer/tradenameCell Marque
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
同位素/亚型IgG
控制melanoma, skin melanocytes
运输wet ice
储存温度2-8℃
可视化nuclear

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