Anti-Rheb-GTP Mouse Monoclonal Antibody
| 型号: | Rheb | | 货号: | 26910 | | 品牌: | NewEast Biosciences | | 参考价格: | 4800 | | 包装: | 30微升 | | 交货期: | 现货 |
包装与价格： | 订货号 | 纯度规格 | 包装 | 价格(元) | | 26910 | | 30微升 | 4800 |
产品名称 Rheb-GTP active小鼠单抗
Rheb-GTP小鼠单抗
产品介绍
GTP酶是GTP/GDP结合蛋白。被细胞表面受体(GPCR)激活后, 它能调节下游效应器的功能。它可以结合GTP、水解GTP，因此在激活的GTP结合状态和非激活的GDP结合状态之间切换。它具有内在的GTP酶活性，可将GTP水解为GDP，从而使G蛋白失活。我们精心筛选的小鼠单克隆抗体能捕捉到与GTP结合的具有活性的GTP酶。它们已被用于通过免疫组织化学监测细胞和组织中 G 蛋白的活化和分布。
| 描述: Anti-Rheb-GTP Monoclonal Antibody | | 背景介绍: Small GTPases are a super-family of cellular signaling regulators. Rheb is a member of the Ras-superfamily GTPases. Rheb has been shown to interact with C-Raf, Mammalian target of rapamycin (mTOR), TSC2, Ataxia telangiectasia mutated (ATM), KIAA1303 and Ataxia telangiectasia and Rad3 related (ATR). | | 免疫原: Recombinant full-length protein of active Rheb. | | 经过测试的应用: IP, IHC,IF | 推荐稀释比:
IP: 1 μg for 1~2 mg total cellular proteins
IHC, IF: 1:50-1:250 |
| 种属反应性: Anti-Rheb-GTP monoclonal antibody recognizes active Rheb of vertebrates. | | 储存条件: Store at -20°C. Avoid freeze/thaw cycles | 免疫沉淀/蛋白质印迹: 
Rheb activation assay. Purified Rheb proteins were immunoprecipitated after treated with GDP (lane 1) or GTPγS (lane 2). Immunoprecipitation was done with the anti-Rheb-GTP monoclonal antibody (Cat. No. 26910). Immunoblot was with an anti-Rheb rabbit polyclonal antibody (Cat. No. 21098). |
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