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| 首页\化工字典\CAS NO:848193-72-6 |
| CAS: | 848193-72-6 | |||
| 分子式: | C14H15ClN2O | |||
| 分子量: | 262.73 | |||
| 英文名称: |
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| 用途: | CHIC-35 is cell-permeable, metabolically stable, and very potent inhibitor of SIRT1; IC50 of S-isomer is 60 nM; IC50 of mixed isomers is 124 nM. There is no inhibition of SIRT3 or HDAC. The IC50 for SIRT2 is 2.77 μM. Sirtuins are protein deacetylases, which represent a new class of histone deacetylases (HDAC) involved in gene silencing. SIRT modulators are potential therapeutics for cancer, diabetes, muscle differentiation, heart failure, neurodegeneration, and aging. |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||
| C921209 | MACKLIN | （6S）-2-氯-5,6,7,8,9,10-六氢环庚[b]吲哚-6-羧酰胺 | 97% (chiral, HPLC) | 1530元/1mg; 5999元/5mg; 17999元/25mg; | 展开 | ||
储存：2-8°C 状态：白色固体 | |||||||