CAS NO:839706-07-9; gnf-7

CAS:

839706-07-9

分子式:

C₂₈H₂₄F₃N₇O₂

分子量:

547.53

英文名称:

gnf-7

n-[3-[1,4-dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2h)-yl]-4-methylphenyl]-3-(trifluoromethyl)-benzamide

n-(4-methyl-3-(1-methyl-7-(6-methylpyridin-3-ylamino)-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4h)-yl)phenyl)-3-(trifluoromethyl)benzamide

用途:

GNF-7 抑制 Bcr-Abl WT 和 Bcr-Abl T315I, IC50 分别为133 nM 和 61 nM。

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