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首页\化工字典\CAS NO:67526-95-8
CAS: 67526-95-8
分子式: C34H50O12
分子量: 650.76
闪点: 188.6 ℉ - closed cup
英文名称: 
thapsigargin
用途: Thapsigargin is a cell-permeable sesquiterpene lactone found in the roots of Thapsia garganica. It is a tumor promoter and induces the release of intracellular stored Ca2+ without hydrolysis of inositolphospholipids via inhibition of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA; IC50=30 nM). It may be used to distinguish between discrete intracellular Ca2+ pools. Thapsigargin-induced tumor promotion and down regulation of the EGF receptor is independent of protein kinase C activation.
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T863962MACKLIN毒胡萝卜素95%593元/1mg;   2380元/5mg;   6638元/25mg;   展开
储存:-20°C
状态:固体
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