CAS NO:62-68-0; beta-diethylaminoethyl diphenylpropylacetate hydrochloride

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CAS:

62-68-0

分子式:

C23H31NO2.HCl

分子量:

389.96

熔点:

122 - 123 °C

英文名称:

beta-diethylaminoethyl diphenylpropylacetate hydrochloride

diethylaminoethanol ester of diphenylpropylacetic acid hydrochloride

nsc 39690

pentanoic acid, 2,2-diphenyl-, 2-(n,n-diethylamino)ethyl ester, hydrochloride

proadifen hydrochloride

propyladiphenin

skf 525a

u 5446

α-Phenyl-α-propylbenzeneacetic acid 2-(diethylamino)ethyl ester

valeric acid, 2,2-diphenyl-, 2-(diethylamino)ethyl ester, hydrochloride

2'-diethylaminoethyl 2,2-diphenylpentanoate hydrochloride

2-diethylaminoethyl 2,2-diphenylvalerate hydrochloride

2-diethylaminoethyl alpha,alpha-diphenyl valerate hydrochloride

5171 rp

alpha-phenyl-alpha-propyl-benzeneacetic aci 2-(diethylamino)ethyl ester h

展开更多英文名称

用途:

SKF-525A HCl (Proadifen) has many biochemical functions, some of which include: inhibitory effects on NOS1 (neuronal nitric oxide synthase; IC50 = 90 mM), adult mouse skeletal muscle AChR (acetyl choline receptor), hepatic drug metabolism via the CYP (cytochrome P450) system, CYP-dependent (cytochrome P450-dependent) arachidonate metabolism (90% at 50 μM), transmembrane calcium influx, and platelet thromboxane synthesis. This compound has also been shown to block KIR6.1 (ATP-sensitive inward rectifier potassium channel 8; IC50 = 4.4 mM) and stimulate endothelial cell prostacyclin production.

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