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CAS: 62-68-0
分子式: C23H31NO2.HCl
分子量: 389.96
熔点: 122 - 123 °C
英文名称: 
beta-diethylaminoethyl diphenylpropylacetate hydrochloride
diethylaminoethanol ester of diphenylpropylacetic acid hydrochloride
nsc 39690
pentanoic acid, 2,2-diphenyl-, 2-(n,n-diethylamino)ethyl ester, hydrochloride
proadifen hydrochloride
propyladiphenin
skf 525a
u 5446
α-Phenyl-α-propylbenzeneacetic acid 2-(diethylamino)ethyl ester
valeric acid, 2,2-diphenyl-, 2-(diethylamino)ethyl ester, hydrochloride
2'-diethylaminoethyl 2,2-diphenylpentanoate hydrochloride
2-diethylaminoethyl 2,2-diphenylvalerate hydrochloride
2-diethylaminoethyl alpha,alpha-diphenyl valerate hydrochloride
5171 rp
alpha-phenyl-alpha-propyl-benzeneacetic aci 2-(diethylamino)ethyl ester h
用途: SKF-525A HCl (Proadifen) has many biochemical functions, some of which include: inhibitory effects on NOS1 (neuronal nitric oxide synthase; IC50 = 90 mM), adult mouse skeletal muscle AChR (acetyl choline receptor), hepatic drug metabolism via the CYP (cytochrome P450) system, CYP-dependent (cytochrome P450-dependent) arachidonate metabolism (90% at 50 μM), transmembrane calcium influx, and platelet thromboxane synthesis. This compound has also been shown to block KIR6.1 (ATP-sensitive inward rectifier potassium channel 8; IC50 = 4.4 mM) and stimulate endothelial cell prostacyclin production.
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