CAS NO:59721-29-8; 4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-benzeneacetic aci 2-(dimethylam

CAS:

59721-29-8

分子式:

C₂₀H₂₂N₄O₅.CH₄O₃S

分子量:

494.52

熔点:

165° C

英文名称:

4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-benzeneacetic aci 2-(dimethylam

ino)-2- oxoethyl ester, monomethanesulfonate

camostat mesylate

n,n-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate methanesul

p-(p-guanidinobenzoyloxy)phenyl acetic acid, n,n-dimethylcarbamoylmethyl este

benzeneacetic acid,4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-, 2-(dimethylamino)-2-oxoethyl ester, monomethanesulfonate

用途:

Camostat Mesilate是胰蛋白酶样的蛋白酶抑制剂，抑制上皮细胞钠离子通道(ENaC)功能，IC50为50 nM, 对Trypsin, Prostasin 和 Matriptase作用效果稍弱。