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CAS: | 519178-28-0 |
分子式: | C20H16F3N7O2 |
分子量: | 443.38 |
中文名称: | n2-(间三氟苄基),n6-(对硝基苄基)嘌呤; n6-[(4-硝基苯基)甲基] -n2-[[3-(三氟甲基)苯基]甲基] -9h-嘌呤-2,6-二胺;n6-[(4-硝基苯基)甲基] -n2-[[3-(三氟甲基)苯基]甲基] -1h-嘌呤-2,6-二胺 |
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英文名称: | tnp | n2-(m-trifluorobenzyl), n6-(p-nitrobenzyl)purine; n6-[(4-nitrophenyl)methyl]-n2-[[3-(trifluoromethyl)phenyl]methyl]-9h-purine-2,6-diamine; n6-[(4-nitrophenyl)methyl]-n2-[[3-(trifluoromethyl)phenyl]methyl]-1h-purine-2,6-diamine |
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用途: | TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 values of 0.55 μM and 10.2 μM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes. |