CAS NO:372196-67-3; 2-甲基-5-硝基-1-苯磺酰[2-[(6-溴咪唑并[1,2-a]吡啶-3-基)亚甲基]-1-甲基肼]

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CAS:

372196-67-3

分子式:

C₁₆H₁₄BrN₅O₄S

分子量:

452.28

中文名称:

2-甲基-5-硝基-1-苯磺酰[2-[(6-溴咪唑并[1,2-a]吡啶-3-基)亚甲基]-1-甲基肼]

英文名称:

n'-((6-bromoimidazo[1,2-a]pyridin-3-yl)methylene)-n,2-dimethyl-5-nitrobenzenesulfonohydrazide

用途:

PIK-75 is a selective cell-permeable inhibitor of PI 3-kinase p110α (IC50 values are 5.8, 76 nM and 1.3 μM at PI 3-kinase p110α, PI 3-kinase p110γ and PI 3-kinase p110β respectively). Inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of