CAS NO:212844-53-6; purvalanol a

CAS:

212844-53-6

分子式:

C₁₉H₂₅ClN₆O

分子量:

388.89

英文名称:

purvalanol a

2-(1R-isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine

ng-60

用途:

Purvalanol A(NG-60)是CDKs高效细胞渗透性抑制剂，对cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1和Cdk5-p35的IC50值分别为4, 70, 35, 850和75 nM。