CAS NO:211364-78-2; r18 三氟醋酸盐

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CAS:

211364-78-2

分子式:

C₁₀₁H₁₅₇N₂₇O₂₉S₃

分子量:

2309.69

中文名称:

r18 三氟醋酸盐

英文名称:

r18 trifluoroacetate

phcvprdlswldleanmclp trifluoroacetate

l-prolyl-l-histidyl-l-cysteinyl-l-valyl-l-prolyl-l-arginyl-l-a-aspartyl-l-leucyl-l-seryl-l-tryptophyl-l-leucyl-l-a-aspartyl-l-leucyl-l-a-glutamyl-l-alanyl-l-asparaginyl-l-methionyl-l-cysteinyl-l-leucyl-l-proline trifluoroacetate

pro-his-cys-val-pro-arg-asp-leu-ser-trp-leu-asp-leu-glu-ala-asn-met-cys-leu-pro trifluoroacetate

用途:

R18 is a peptide antagonist of 14-3-3, potently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and abolishes the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1.