| |
| 首页\化工字典\CAS NO:1951431-22-3 |
| CAS: | 1951431-22-3 | |
| 分子式: | C23H27N7O | |
| 分子量: | 417.510 | |
| 中文名称: |
| |
| 用途: | BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves. |