| 英文名称: | | n-(2-((4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl)methyl)-1-oxo-3-glycin | | dihydrate, (3R-(1(s*),3-alpha,4-alpha))-phen ylpropyl) | | ly 246736 dihydrate | | n-(2-((4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl)methyl)-1-oxo-3-phen ylpropyl)-,dihydrate, (3Rglycin |
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| 用途: | Alvimopan (LY-246736) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors. |
