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| 首页\化工字典\CAS NO:1646839-59-9 |
| CAS: | 1646839-59-9 | |
| 分子式: | C32H26N4O6 | |
| 分子量: | 562.570 | |
| 中文名称: |
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| 用途: | ONO-7475 is a potent, selective, and orally active novel Anexelekto/MER tyrosine kinase inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively. ONO-7475 sensitizes AXL-overexpressing EGFR-mutant NSCLC cells to the EGFR-TKIs, suppresses the emergence and maintenance of tolerant cells. ONO-7475 combines with Osimertinib (HY-15772) provides a bright promise for the study of EGFR-mutated non-small cell lung cancer (NSCLC). |