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| 首页\化工字典\CAS NO:1394371-75-5 |
| CAS: | 1394371-75-5 | |
| 分子式: | C20H18ClNO3S2 | |
| 分子量: | 419.940 | |
| 中文名称: |
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| 用途: | nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 µM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease. |