CAS NO:136087-85-9; spiro(4h-1-benzopyran-4,4'-imidazolidine)-2-carboxamide, 2,3-dihydro-2',5'-diox

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CAS:

136087-85-9

分子式:

C₁₂H₁₀FN₃O₄

分子量:

279.22

英文名称:

spiro(4h-1-benzopyran-4,4'-imidazolidine)-2-carboxamide, 2,3-dihydro-2',5'-diox

(2S-cis)-o-6-fluoro

(2S,4S)-6-fluoro-2',5'-dioxospiro(3,4-dihydro-2h-1-benzopyran-4,4'-imida zoli

dine)-2-carboxamid

snk 860

3-dihydro-2',5'-dioxo-6-fluoro-4'-imidazolidine)-2-carboxamid (2S-cis)-spiro(4h-1-benzopyran-2

用途:

Fidarestatis an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat has anti-diabetic activity.