CAS NO:1357349-91-7; spp86

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CAS:

1357349-91-7

分子式:

C₁₆H₁₅N₅

分子量:

277.32

英文名称:

spp86

1-isopropyl-3-(phenylethynyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine

用途:

SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling.