CAS NO:1355326-35-0; agi-5198

CAS:

1355326-35-0

分子式:

C₂₇H₃₁FN₄O₂

分子量:

462.56

英文名称:

agi-5198

n-[2-(cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-n-(3-fluorophenyl)-2-methyl-1h-imidazole-1-acetamide

idh-c35

n-cycohexyl-2-(n-(3-fluorophenyl)-2-(2-methyl-1h-imidazol-1-yl)acetamido)-2-(o-tolyl)acetamide

用途:

AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM.