CAS NO:133825-81-7; urea, n-(2,6-bis(1-methylethyl)phenyl)-n'-((1-(4-(dimethylamino)phenyl)cyclopen

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CAS:

133825-81-7

分子式:

C₂₇H₄₀ClN₃O

分子量:

458.08

英文名称:

urea, n-(2,6-bis(1-methylethyl)phenyl)-n'-((1-(4-(dimethylamino)phenyl)cyclopen

n-(2,6-bis(1-methylethyl)phenyl)-n'-((1-(4-(dimethylamino)phenyl)cyclope ntyl

)methyl)urea hcl

pd 132301-2

n-(2,6-bis(1-methylethyl)phenyl)-n'-((1-(4-(dimethylamino)phenyl)cyclopent yl)methyl)-ure monohydrochloride

用途:

Nevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) 是一种有效的选择性酰基辅酶 A：胆固醇 O-酰基转移酶 1 (ACAT1) 抑制剂，EC50 为 9 nM。Nevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) 抑制 ACAT2，EC50 为 368 nM。