CAS NO:1144068-46-1; n-[4-[1-(1,4-dioxaspiro[4.5]dec-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1h-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-n′-methyl-urea

CAS:

1144068-46-1

分子式:

C₂₇H₃₃N₇O₄

分子量:

519.6

中文名称:

n-[4-[1-(1,4-dioxaspiro[4.5]dec-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1h-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-n′-methyl-urea

英文名称:

wye-125132

wye-132

用途:

WYE-125132 (WYE-132)是一种高度有效的，ATP竞争性的mTOR抑制剂，IC50为0.19 nM；作用于mTOR比作用于PI3Ks或PI3K相关激酶hSMG1和ATR选择性高。

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