CAS NO:105628-72-6; hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-1h-4-diazepine

CAS:

105628-72-6

分子式:

C₁₄H₁₇N₃O₃S

分子量:

307.37

英文名称:

hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-1h-4-diazepine

1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine

ha 1100

hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-1h-1,4-diazepi ne

hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-1h-4-diazepine

用途:

Hydroxyfasudil(HA1100)是Fasudil的代谢物，对ROCK1和ROCK2的IC50分别为120nM和170nM，还是血管舒张剂。