产品介绍：
产品说明
生化/生理作用
Fosaprepitant dimeglumine acts as a therapeutic agent to treat chemotherapy-induced nausea and vomiting. It also acts as a weak inhibitor of cytochrome P450 3A4 (CYP3A4).
Fosaprepitant dimeglumine is a Substance P/neurokinin-1 (NK1) receptor antagonist. It is a water soluble prodrug of the antiemetic drug aprepitant.
基本信息
| 经验(实验)分子式 | C23H22F7N4O6P · C14H34N2O10 |
| 分子量 | 1004.83 |
| NACRES | NA.77 |
产品性质
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 旋光性 | [α]/D +27 to +34°, c = 0.5 in methanol |
| 储存条件 | desiccated |
| 颜色 | white to beige |
| 溶解性 | H2O: 2 mg/mL, clear |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| SMILES string | FC1=CC=C([C@@H]2N(CCO[C@@H]2O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)CC(NC4=O)=NN4P(O)(O)=O)C=C1.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
