产品说明
一般描述
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
免疫原
A phospho specific peptide corresponding to residues surrounding Y493 of human ZAP70
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | liquid |
| species reactivity | human |
| 浓度 | 2.66 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt登记号 | P43403 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ZAP70(7535) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
