产品说明
一般描述
Diacylglycerol/diglyceride (DAG) is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage.
应用
18:1 DG has been used as a diacyl-glycerol source in diacylglycerol O-acyltransferase 1 (DGAT1) assay. It has also been used as substrate to assess compounds as potential inhibitors of DGAT-1 in DGAT-1 enzyme assay. It is suitable to use in lipid-protein overlay screen assay with the recombinant protein His-AtROP6.
包装
5 mL PTFE Vial with Screw Cap (800811O-10mg)
5 mL PTFE Vial with Screw Cap (800811O-200mg)
5 mL PTFE Vial with Screw Cap (800811O-25mg)
5 mL PTFE Vial with Screw Cap (800811O-500mg)
储存及稳定性
Diacylglycerols are conveniently stored in chloroform solutions in glass vials with PTFE-lined caps at -20℃. Under these conditions acyl migration is minimal. Avoid plastic when handling chloroform solutions.
其他说明
Effective concentration:
Most biological responses saturate at 20 to 250 μM sn-1,2-dioctanoylglycerol. Only sn-1,2 isomers appear to be active.
Delivery to cells:
Dry samples of diacylglycerol in chloroform, using a stream of nitrogen. Dissolve the residue in an appropriate volume of ethanol or DMSO, then dilute to the desired aqueous medium.
Precaution: Since short chain Diacylglycerols mimic effects of the tumor-promoting phorbol diesters in a number of biological systems, extra care should be employed in their handling. Treatment of solutions, vessels and other articles with 1N NaOH before washing or discarding will destroy diacylglycerols.
基本信息
| 经验(实验)分子式 | C39H72O5 |
| 分子量 | 620.99 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 包装 | pkg of 1 × 10 mg (with screw cap (800811O-10mg)) pkg of 2 × 100 mg (with screw cap (800811O-200mg)) pkg of 5 × 100 mg (with screw cap 800811O-500mg) pkg of 1 × 25 mg (with screw cap (800811O-25mg)) |
| manufacturer/tradename | Avanti Polar Lipids 800811O |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| InChI | 1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,37,40H,3-16,21-36H2,1-2H3/b19-17+,20-18-/t37-/m0/s1 |
| InChI key | AFSHUZFNMVJNKX-CSWDEDFYSA-N |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
