产品介绍：
产品说明
应用
α-(Methylamino)isobutyric acid (MeAIB) has been used:
- as a system A transport system inhibitor to perform inhibition experiments
- as a system A transport system inhibitor to study its effect on the generation of epileptiform field potentials (EFPs) in the acutely disinhibited cortical slices
- as an N-acetyltransferase (SNAT) inhibitor in Hank′s balanced salt solution (HBSS) to study its influence on the uptake of 14C-cysteine/ radioactive-labeled cysteine
包装
250 mg in poly bottle
1 g in poly bottle
生化/生理作用
α-(Methylamino)isobutyric acid (MeAIB), a competitive inhibitor of the neutral amino acid transport A system, is an N-methylated substrate. It is capable of decreasing the amplitude of the miniature excitatory postsynaptic current (mEPSC) in hippocampus neurons developing on top of astrocytes. MeAIB can block the alanine-proline (AP) pathway.
基本信息
| 线性分子式 | CH3NHC(CH3)2COOH |
| 分子量 | 117.15 |
| Beilstein | 1746984 |
| EC 号 | 219-898-2 |
| MDL编号 | MFCD00004191 |
| PubChem化学物质编号 | 24896726 |
| NACRES | NA.26 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97% (titration) |
| 形式 | powder |
| technique(s) | ligand binding assay: suitable |
| 颜色 | white |
| mp | >300 ℃ (lit.) |
| 储存温度 | −20℃ |
| SMILES string | CNC(C)(C)C(O)=O |
| InChI | 1S/C5H11NO2/c1-5(2,6-3)4(7)8/h6H,1-3H3,(H,7,8) |
| InChI key | DLAMVQGYEVKIRE-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H319 |
| 预防措施声明 | P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
