产品介绍：
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
XAP044 is a brain penetrant, potent and selective mGlu7 (metabotropic glutamate receptor subtype 7) antagonist that inhibits lateral amygdala long-term potentiation (LTP) in brain slices from wild type mice. XAP044 binds to a pocket localized in mGlu7′s extracellular Venus flytrap domain (VFTD) close to the binding site of the orthosteric agonist L-glutamate. XAP044 exhibits a wide-spectrum anti-stress, antidepressant- and anxiolytic-like efficacy in rodent behavioral model.
其他说明
Light sensitive. This compound has Iodine and should be kept in the dark.
基本信息
| 经验(实验)分子式 | C15H9IO4 |
| 分子量 | 380.13 |
| MDL编号 | MFCD00525548 |
| PubChem化学物质编号 | 329825781 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | protect from light |
| 颜色 | white to beige |
| 溶解性 | DMSO: 20 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | O=C1C(OC2=CC=C(I)C=C2)=COC3=C1C=CC(O)=C3 |
| InChI | 1S/C15H9IO4/c16-9-1-4-11(5-2-9)20-14-8-19-13-7-10(17)3-6-12(13)15(14)18/h1-8,17H |
| InChI key | XXZKJJYWINSUMJ-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
