产品介绍：
产品说明
生化/生理作用
Betrixaban is an orally active, active site-targeting, highly potent and selective factor Xa (fXa) inhibitor (IC50 = 1.5 nM; Ki = 117 pM) with much reduced plasma kallikrein inhibitory activity (IC50 = 6.3 μM) and little potency against thrombin, trypsin, t-PA, aPC or plasmin inhibition (IC50 >10 μM). Betrixaban exhibits good pharmacokinetic properties and anticoagulant efficacy against various thromboembolism (VTE) events in vivo.
基本信息
| 经验(实验)分子式 | C23H22ClN5O3 |
| 分子量 | 451.91 |
| MDL编号 | MFCD16038040 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 2 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | ClC1=CN=C(C=C1)NC(C2=C(NC(C3=CC=C(C(N(C)C)=N)C=C3)=O)C=CC(OC)=C2)=O |
安全信息
| 象形图 |   |
| 警示用语： | Warning |
| 危险声明 | H302 - H373 |
| 预防措施声明 | P301 + P312 + P330 - P314 |
| 危险分类 | Acute Tox. 4 Oral - STOT RE 2 |
| 靶器官 | Blood |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
