产品介绍：
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
CC-401 is a cell penetrant, potent and selective c-Jun N terminal kinase (JNK) inhibitor that blocks JNK signaling in the rat obstructed kidney and inhibits renal fibrosis in the unilateral ureteral obstruction model. CC-401 in combination with chemotherapy exhibits synergism in colon cancer cell lines.
基本信息
| 经验(实验)分子式 | C22H24N6O · 2HCl |
| 分子量 | 461.39 |
| MDL编号 | MFCD21364765 |
| PubChem化学物质编号 | 329825499 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | H2O: 10 mg/mL, clear |
| 储存温度 | −20℃ |
| SMILES string | [H]Cl.C1(C2=NC=NN2)=CC3=C(NN=C3C4=CC=CC(OCCN5CCCCC5)=C4)C=C1 |
| InChI | 1S/C22H24N6O.ClH/c1-2-9-28(10-3-1)11-12-29-18-6-4-5-16(13-18)21-19-14-17(22-23-15-24-27-22)7-8-20(19)25-26-21;/h4-8,13-15H,1-3,9-12H2,(H,25,26)(H,23,24,27);1H |
| InChI key | OIBVXKYKWOUGAO-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
