|
GEN1蛋白抗体
产品名称 Anti-Gen1 Anti-GEN1, Holliday junction 5' flap endonuclease Antibody 产品介绍
靶标: Gen1 产品别名: 5830483C08Rik; Gen1; GEN1, Holliday junction 5' flap endonuclease; GEN1, Holliday junction 5' flap endonuclease; flap endonuclease GEN homolog 1; Gen homolog 1, endonuclease; GEN1蛋白; 背景信息: This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016], |
广州伟伯科技有限公司
手机: 13533759269 传真: 020-36393398 联系人: 林生 邮编: 362011 地址: 广州市白云区石井石槎路金碧新城5栋904室 相关产品:
|