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重组精神障碍相关GAP蛋白
产品名称 Recombinant SRGAP3 Recombinant SLIT-ROBO Rho GTPase activating protein 3 protein 产品介绍
基因名: SRGAP3 产品别名: ARHGAP14; MEGAP; SRGAP2; WRP; SRGAP3; SLIT-ROBO Rho GTPase activating protein 3; SLIT-ROBO Rho GTPase activating protein 3; SLIT-ROBO Rho GTPase-activating protein 3; SLIT-ROBO Rho GTPase activating protein 2; WAVE-associated Rac GTPase activating protein; mental disorder-associated GAP; rho GTPase-activating protein 14; 精神障碍相关GAP蛋白; 背景信息: srGAP3 (SLIT ROBO Rho GTPase-activating protein 3) is a GTPase activating protein (GAP) for the small G protein Rac. It has a putative role in attenuating Rac1 signalling in neurons. srGAP3 is thought to act downstream of the Slit-Robo pathway, which regulates neuronal migration and axonal branching, and play an important role in axonal regeneration after axotomy. It also plays a putative role in severe mental retardation. |
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