产品介绍：
产品说明
一般描述
4-Hydroxytamoxifen is a first generation, selective estrogen receptor modulator (SERM) that functions as an antagonist in breast cancer cells but can display estrogen-like activities in the uterus and bone.
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
4-Hydroxytamoxifen may be used as a reference standard in the determination of 4-hydroxythmoxifen in plasma samples using high-performance liquid chromatography with fluorescence detection (HPLC).
生化/生理作用
化疗药物他莫西芬的代谢物，表现出比原药更强效的雌激素激动剂/拮抗剂活性。还是脂质过氧化的活性膜内抑制剂。
基本信息
| 经验(实验)分子式 | C26H29NO2 |
| 分子量 | 387.51 |
| NACRES | NA.24 |
产品性质
| 等级 | analytical standard |
| 质量水平 | 100 |
| 测定 | ≥97.5% (HPLC) |
| 保质期 | limited shelf life, expiry date on the label |
| technique(s) | HPLC: suitable gas chromatography (GC): suitable |
| 杂质 | ≤5.0% water |
| application(s) | forensics and toxicology pharmaceutical (small molecule) |
| 格式 | neat |
| SMILES string | CC\C(c1ccccc1)=C(/c2ccc(O)cc2)c3ccc(OCCN(C)C)cc3.CC\C(c4ccccc4)=C(\c5ccc(O)cc5)c6ccc(OCCN(C)C)cc6 |
| InChI | 1S/2C26H29NO2/c2*1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h2*5-17,28H,4,18-19H2,1-3H3/b26-25+;26-25- |
| InChI key | ZJLDABGSDWXVGE-BDSXMVAQSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Warning |
| 危险声明 | H302 + H312 + H332 - H361 |
| 预防措施声明 | P201 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313 |
| 危险分类 | Acute Tox. 4 Oral - Repr. 2 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
