产品说明
一般描述
GRK1 (rhodopsin kinase) is an enzyme that belongs to serine/threonine protein kinase family and expresses mainly in rod and cone photoreceptors. It has a crucial role in phosphorylation of photoactivated rhodopsin and hence starting steps in its deactivation. Monoclonal anti-rhodopsin kinase 1a antibody can be used in immunoprecipitation. Mouse anti-rhodopsin kinase 1a antibody reacts specifically with an epitope present in the C-terminal region of mouse, bovine, rat, chicken and human GRK1a. The product has shown no cross-reactivity with other G protein coupled kinases together with GRK1b.
免疫原
derived from human GRK1
应用
Monoclonal anti-rhodopsin kinase 1a antibody can be used in indirect immunofluorescence and western blotting.
目标描述
Rhodopsin Kinase 1A encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation.
外形
Supplied in phosphate buffered saline containing 0.05% sodium azide.
基本信息
| MDL编号 | MFCD03457575 |
| NACRES | NA.44 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | G8, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | rat, bovine, human, mouse, chicken |
| technique(s) | immunoprecipitation (IP): suitable indirect immunofluorescence: suitable western blot: suitable |
| UniProt登记号 | Q15835 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... GRK1(6011) mouse ... Grk1(24013) rat ... Grk1(81760) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
