产品说明
一般描述
Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [2].
Also available Fmoc-Lys(Dde)-OH 852057.
This derivative has been employed in Fmoc SPPS to facilitate the introduction of biotin to the side-chain of lysine [3].
The product number for this product was previously 04-12-5201.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
联系
Replaces: 04-12-5201
分析说明
Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(157B)): ≥ 97 %
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 96.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 1.00 %
For TLC-Systems see our General Catalog
法律信息
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C31H36N2O6 |
| 分子量 | 532.63 |
产品性质
| 质量水平 | 200 |
| 产品线 | Novabiochem® |
| 测定 | ≥90.0% (acidimetric) ≥96.0% (HPLC) ≥97% (TLC) |
| 形式 | powder |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| manufacturer/tradename | Novabiochem® |
| mp | >70 ℃ (decomposition) |
| 官能团 | Fmoc |
| 储存温度 | 15-25℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
