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CITED1 (5H6) Mouse Monoclonal Antibody

品牌
Sigma-Aldrich
货号
424M-1
包装型号
规格纯度
价格
2271.2 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

CITED1 is a transcriptional cofactor expressed in the metanephric mesenchyme (MM) of the embryonic kidney and is down-regulated as these cells undergo epithelial differentiation.1-4 It is thought that CITED1 may play a role in maintaining MM cells in an undifferentiated state.3 Wilms′ tumors (WT) are thought to arise from abnormal postnatal retention and dysregulated differentiation of nephrogenic progenitor cells that originate as a condensed MM within embryonic kidneys.1 CITED1 expression has been shown to persist in blastemal cell populations of human WT.1,2 In the developing embryonic kidney, CITED1 expression is seen in the cytoplasmic compartment. In WT, expression of CITED1 is detected in the nuclear compartment of tumor cells.1-4 It has been suggested that persistent expression of CITED1 in the MM could play a role in WT initiation and pathogenesis.1 CITED1 has been detected in 86.8% of WT Cases.2

质量


IVD

IVD

IVD

RUO

联系

CITED1 Positive Control Slides, Product No. 424S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.41

产品性质

质量水平500
100
生物来源mouse
偶联物unconjugated
抗体形式ascites fluid
antibody product typeprimary antibodies
克隆5H6, monoclonal
描述 (For In Vitro Diagnostic Use in Select Regions (See Chart))
形式buffered aqueous solution
species reactivityhuman
包装vial of 0.1 mL concentrate (424M-14)
vial of 0.5 mL concentrate (424M-15)
bottle of 1.0 mL predilute (424M-17)
vial of 1.0 mL concentrate (424M-16)
bottle of 7.0 mL predilute (424M-18)
manufacturer/tradenameCell Marque
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同位素/亚型IgG2aκ
控制Wilms’ tumor
运输wet ice
储存温度2-8℃
可视化nuclear

Sigma-Aldrich

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