Sep-Pak Alumina A Vac cartridges contain a highly active grade of alumina with an acidic surface chemistry. The aluminum oxide surface provides an extremely polar surface for analyte retention and has properties of a Lewis acid. This normal phase sorbent is similar in use to silica; however, it is slightly more stable than unfunctionalized silica under high pH conditions. This acidic alumina is also low-capacity ion exchanger in aqueous media. Unlike polymer-based ion exhangers, this sorbent is unaffected by high-energy radioactivity and can be used for radioactive compound isolation. These syringe-barrel-type cartridges are designed for use with vacuum manifolds and automated SPE instruments.

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