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突触核膜蛋白4抗体
产品名称 Anti-SYNE4 Anti-spectrin repeat containing nuclear envelope family member 4 Antibody 产品介绍
靶标： SYNE4 产品别名： C19orf46； DFNB76； KASH4； Nesp4； SYNE4； spectrin repeat containing nuclear envelope family member 4； spectrin repeat containing nuclear envelope family member 4； nesprin-4； KASH domain-containing protein 4； deafness, autosomal recessive 76； nuclear envelope spectrin repeat protein 4； 突触核膜蛋白4； 背景信息： C19orf46 is a 404 amino acid single-pass type IV membrane protein that belongs to the nesprin family. C19orf46 partcipates in the establishment of secretory epithelial morphology by inducing kinesin-dependent apical migration of the centrosome and Golgi apparatus as well as basal localization of the nucleus. C19orf46 interacts with UKHC and KCL1, and exists as two alternatively spliced isoforms. C19orf46 contains a KASH domain, which consists of a transmembrane motif, mediates nuclear enevelop targeting and binds to the SUN domain of SUN1 and SUN2. C19orf46 is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA. |
广州伟伯科技有限公司
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