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跨膜蛋白KREMEN2抗体
产品名称 Anti-Kremen2 Anti-kringle containing transmembrane protein 2 Antibody 产品介绍
靶标： Kremen2 产品别名： 2900054E04Rik； Krm2； Kremen2； kringle containing transmembrane protein 2； kringle containing transmembrane protein 2； kremen protein 2； dickkopf receptor 2； kringle domain-containing transmembrane protein 2； kringle-containing protein marking the eye and the nose； 跨膜蛋白KREMEN2； 背景信息： This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. |
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