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膜相关接头蛋白LAX抗体
产品名称 Anti-LAX1 Anti-lymphocyte transmembrane adaptor 1 Antibody 产品介绍
靶标： LAX1 产品别名： LAX； LAX1； lymphocyte transmembrane adaptor 1； lymphocyte transmembrane adaptor 1； lymphocyte transmembrane adapter 1； LAT-like membrane associated protein； linker for activation of x cells； membrane-associated adapter protein LAX； 膜相关接头蛋白LAX； 背景信息： function:Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.,induction:Up-regulated in T-cells following TCR engagement.,PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines., |
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