This gene encodes one ofThe subunits ofThe intraflagellar transport (IFT) complex A. Intraflagellar transport is involved inThe genesis, resorption and signaling of primary cilia.The primary cilium is a microtubule-based sensory organelle atThe surface of most quiescent mammalian cells, that receives signals from its environment, such asThe flow of fluid, light or odors, and transduces those signals toThe nucleus. Loss ofThe corresponding protein in mouse results in renal cystic disease. [provided by RefSeq, Jun 2012]