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重组NLRP11蛋白
产品名称 Recombinant NLRP11 Recombinant NLR family pyrin domain containing 11 protein 产品介绍
基因名： NLRP11 产品别名： CLR19.6； NALP11； NOD17； PAN10； PYPAF6； PYPAF7； NLRP11； NLR family pyrin domain containing 11； NLR family pyrin domain containing 11； NACHT, LRR and PYD domains-containing protein 11； NACHT, leucine rich repeat and PYD containing 11； PAAD- and NACHT-containing protein 10B； PAAD-and NACHT domain-containing protein 10； PYRIN-containing APAF1-like protein 6； nucleotide-binding oligomerization domain protein 17； nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11； NLRP11蛋白； 背景信息： NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008] |
广州伟伯科技有限公司
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