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重组腺瘤性息肉调节蛋白
产品名称 Recombinant APCDD1 Recombinant APC down-regulated 1 protein 产品介绍
基因名： APCDD1 产品别名： B7323； DRAPC1； FP7019； HHS； HTS； HYPT1； APCDD1； APC down-regulated 1； APC down-regulated 1； protein APCDD1； adenomatosis polyposis coli down-regulated 1 protein； hypoptrichosis simplex； 腺瘤性息肉调节蛋白； 背景信息： APCDD1 is a novel protein that has been shown to be a target of Wnt/beta catenin signaling pathway in cancer cell lines. APCDD1 is overexpressed in colorectal carcinogenesis and is deregulated in CTNNB1 mutated Wilms tumors. [FUNCTION] Probably plays a role in colorectal tumorigenesis. May be a developmental target gene of the Wnt/Beta-catenin pathway. [SUBCELLULAR LOCATION] Membrane; Single-pass type I membrane protein (Potential). [TISSUE SPECIFICITY] Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. [INDUCTION] Transcriptionally regulated by the CTNNB1/TF7L2complex. |
广州伟伯科技有限公司
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