KCTD6 (potassium channel tetramerisation domain containing 6) is a 237 amino acid protein that contains one BTB domain, suggesting a possible role as a transcriptional regulator. The gene encoding KCTD6 maps to chromosome 3, which contains over 1,100 genes. Notably, a chemokine receptor gene cluster and a variety of human cancer related loci reside on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells as well.