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重组1号染色体开放阅读框86蛋白
产品名称 Recombinant Faap20 Recombinant Fanconi anemia core complex associated protein 20 protein 产品介绍
基因名： Faap20 产品别名： 2610002J02Rik； Faap20； Fanconi anemia core complex associated protein 20； Fanconi anemia core complex associated protein 20； Fanconi anemia core complex-associated protein 20； FANCA-associated protein of 20 kDa； Fanconi anemia-associated protein of 20 kDa； likely orthologue of H. sapiens chromosome 1 open reading frame 86 (C1orf86)； 1号染色体开放阅读框86； 背景信息： Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1. |
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