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磷酸二酯酶6α抗体
产品名称 Anti-PDE6A Anti-phosphodiesterase 6A Antibody 产品介绍
靶标： PDE6A 产品别名： CGPR-A； PDEA； RP43； PDE6A； phosphodiesterase 6A； phosphodiesterase 6A； rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha； GMP-PDE alpha； PDE V-B1； cGMP phosphodiesterase alpha subunit； phosphodiesterase 6A, cGMP-specific, rod, alpha； retinitis pigmentosa type 43； rod photoreceptor cGMP phosphodiesterase alpha subunit； 磷酸二酯酶6α； 背景信息： This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. |
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