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FGD1蛋白抗体
交货期:1周


产品名称
Anti-FGD1
Anti-FYVE, RhoGEF and PH domain containing 1 Antibody
产品介绍
靶标:

FGD1


产品别名:

AAS; FGDY; MRXS16; ZFYVE3; FGD1; FYVE, RhoGEF and PH domain containing 1; FYVE, RhoGEF and PH domain containing 1; FYVE, RhoGEF and PH domain-containing protein 1; faciogenital dysplasia 1 protein; rho/Rac GEF; rho/Rac guanine nucleotide exchange factor FGD1; zinc finger FYVE domain-containing protein 3; FGD1蛋白;


背景信息:
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011],
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