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重组硫酸软骨素聚合酶3蛋白
交货期:1周

产品名称
Recombinant CHPF2
Recombinant chondroitin polymerizing factor 2 protein
产品介绍
基因名:

CHPF2


产品别名:

CSGLCA-T; CSGlcAT; ChSy-3; chPF-2; CHPF2; chondroitin polymerizing factor 2; chondroitin polymerizing factor 2; chondroitin sulfate glucuronyltransferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; chondroitin synthase-3; 硫酸软骨素聚合酶3;


背景信息:
CSGlcA-T is a 772 amino acid single-pass type II membrane protein of the golgi apparatus that belongs to the chondroitin N-acetylgalactosaminyltransferase family. Widely expressed and existing as two alternatively spliced isoforms, CSGlcA-T is found at highest levels in small intestine, pancreas and placenta, with lower levels in heart, brain, kidney, and skeletal muscle where it transfers glucuronic acid from UDP-glucuronic acid to N-acetylgalactosamine residues of elongating chondroitin polymers. The gene encoding CSGlcA-T maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome and Lissencephaly.
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