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重组小肠钠通道蛋白5
产品名称 Recombinant ASIC5 Recombinant acid sensing ion channel subunit family member 5 protein 产品介绍
基因名: ASIC5 产品别名: ACCN5; HINAC; INAC; ASIC5; acid sensing ion channel subunit family member 5; acid sensing ion channel subunit family member 5; acid-sensing ion channel 5; acid sensing (proton gated) ion channel family member 5; acid sensing ion channel family member 5; amiloride-sensitive cation channel 5, intestinal; amiloride-sensitive sodium channel; human intestine Na(+) channel; 小肠钠通道蛋白5; 背景信息: ACCN5 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. DEG/ENaC superfamily members are amiloride-sensitive sodium channels that contain intracellular N- and C-termini, two hydrophobic transmembrane regions and a cysteine-containing extracellular loop. Localizing to the cell membrane, ACCN5 is a multi-pass membrane protein that is expressed in small intestine, jejunum and duodenum. ACCN5 is also expressed at low levels in rectum and testis. Existing as a homo- or heterotetramer, ACCN5 functions as a Na+-selective cation channel that, characteristic of its family, can be inhibited by amiloride. |
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