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重组p53反应基因3(PRG3)蛋白
产品名称 Recombinant PRG3 Recombinant proteoglycan 3, pro eosinophil major basic protein 2 protein 产品介绍
基因名： PRG3 产品别名： MBP2； MBPH； PRG3； proteoglycan 3, pro eosinophil major basic protein 2； proteoglycan 3, pro eosinophil major basic protein 2； proteoglycan 3； eosinophil major basic protein homolog； prepro-MBPH； prepro-major basic protein homolog； p53反应基因3(PRG3)； 背景信息： Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine and leukotriene C4 release from basophils. |
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