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重组核因子κB抑制蛋白样蛋白2
产品名称 Recombinant TONSL Recombinant tonsoku like, DNA repair protein 产品介绍
基因名: TONSL 产品别名: IKBR; NFKBIL2; SEMDSP; TONSL; tonsoku like, DNA repair protein; tonsoku like, DNA repair protein; tonsoku-like protein; I-kappa-B-related protein; NF-kappa-B inhibitor-like protein 2; ikappaBR; inhibitor of kappa B-related protein; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; 核因子κB抑制蛋白样蛋白2; 背景信息: The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. [provided by RefSeq, Jul 2008] |
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