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重组钾离子通道Kir2.2蛋白
产品名称 Recombinant KCNJ12 Recombinant potassium inwardly rectifying channel subfamily J member 12 protein 产品介绍
基因名: KCNJ12 产品别名: IRK-2; IRK2; KCNJN1; Kir2.2; hIRK; hIRK1; hkir2.2x; kcnj12x; KCNJ12; potassium inwardly rectifying channel subfamily J member 12; potassium inwardly rectifying channel subfamily J member 12; ATP-sensitive inward rectifier potassium channel 12; potassium channel, inwardly rectifying subfamily J, member 12; potassium voltage-gated channel subfamily J member 12; 钾离子通道Kir2.2; 背景信息: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. |
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